Date

6-17-2026

Department

School of Behavioral Sciences

Degree

Doctor of Philosophy in Psychology (PhD)

Chair

Robin Rippeth

Keywords

Anxiety disorders, Anxiety relief, Cannabis, Cannabinoids, Endocannabinoid system

Disciplines

Psychology

Abstract

This mixed-methods study investigated the efficacy of various cannabinoid types and dosages in treating anxiety disorders among young adults (19–23), examining cannabis's role in regulating a deregulated endocannabinoid system. Fourteen participants tracked real-time anxiety symptoms, strain type, dosage, and affective states using the Releaf App. Quantitative analyses included repeated-measures ANOVA and Pearson correlation, complemented by quantitative content analysis of affect descriptors. Key findings revealed a statistically significant reduction in self-reported anxiety symptoms following cannabis use (p < .001, partial 2 = .97), supporting the hypothesis that cannabis can regulate a deregulated endocannabinoid system. No significant differences in anxiolytic effects were observed among Indica, Hybrid Indica/Sativa, and Hybrid Sativa/Indica strains. The optimal dosage for perceived anxiety relief appeared to be higher than initially hypothesized, with a moderate-to-strong association between dosage and anxiety relief (r = .662, p = .0099). Participants overwhelmingly reported positive affective states, such as "calm," "peaceful," and "relaxed," post-cannabis use, with no negative descriptors observed in the analyzed data. These results suggest that cannabis can serve as a short-term coping strategy for anxiety in young adults, leading to perceived emotional regulation.

Download

Included in

Psychology Commons

Share

COinS