Date

5-23-2025

Department

School of Health Sciences

Degree

Doctor of Philosophy in Health Sciences (PhD)

Chair

Chloe Fields

Keywords

clinical trials, Peripheral Artery Disease, recruitment and retention, Black Americans, Awareness, barriers, socioeconomics, cardiovascular diseases, qualitative, narrative, interview, direct perspectives, 40 years old, Newark, New Jersey

Disciplines

Diseases | Public Health

Abstract

The purpose of this qualitative narrative study was to understand Black American men and women 40 years old and over perceptions of participating in clinical trials and evaluating the extent of awareness about Peripheral Artery Disease (PAD). Normative and explanatory theoretical framework was used to set the norms that understand most Black American behavior and explain causes of behaviors. This in turn helped sponsors, investigators, and researchers improve recruitment plans, outreach programs, and increase marketing to attract this population. Using MAXQDA software this research gathered qualitative data from 20 Black American men and women participants 40 years old and over, by conducting face-to-face interviews or virtual interviews in the city of Newark, New Jersey. The results of this study shows that mistrust and lack of knowledge are the leading reasons why Black American men and women over 40 years old and over are not willing to participate in clinical trials. In addition, 65% of participants lacked awareness about Peripheral Artery Disease and only 5% of participants were able to accurately explain the disease.

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