Date

12-11-2024

Department

School of Health Sciences

Degree

Doctor of Philosophy in Health Sciences (PhD)

Chair

Laurel Glover

Keywords

zoonotic spillover, wildlife-human interaction, sub-Saharan Africa, emerging infectious diseases, wildlife consumption

Disciplines

Medicine and Health Sciences

Abstract

Zoonotic spillover, the transmission of infectious pathogens from animals to humans, is a critical public health concern in Sub-Saharan Africa. This study examines the role of wildlife factors in zoonotic spillover within this region, highlighting the complex interplay between human-wildlife interactions, environmental changes, and emerging zoonotic diseases. The research underscores that Sub-Saharan Africa is particularly vulnerable due to its rich biodiversity, cultural practices involving wildlife, and socioeconomic challenges. Factors such as habitat encroachment, wildlife consumption, and inadequate health infrastructure contribute to the heightened risk of zoonotic spillover. The study employs an online survey followed with a contextual analysis, and socioeconomic factors to identify the key drivers of zoonotic outbreaks in the region. It also emphasizes the importance of the "One Health" approach, which advocates for the integration of human, animal, and environmental health strategies to mitigate the risks of zoonotic diseases. The findings reveal that certain wildlife species, particularly bats and primates, are significant reservoirs of zoonotic pathogens, contributing to frequent spillover events. The study calls for strengthened surveillance, improved public health interventions, and sustainable wildlife management practices to reduce the incidence of zoonotic diseases. This research contributes to the broader understanding of zoonotic spillover and its implications for global health security, offering critical insights for policymakers and health professionals working in disease prevention and control in Sub-Saharan Africa.

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