Date

11-13-2024

Department

School of Health Sciences

Degree

Doctor of Philosophy in Health Sciences (PhD)

Chair

Ruth Rasmussen

Keywords

cardiac rehabilitation, high-intensity interval training, cardiovascular disease, exercise prescription, moderate-intensity continuous training, resistance training, functional capacity, clinical risk factors

Disciplines

Rehabilitation and Therapy

Abstract

Moderate-intensity continuous training (MICT), resistance training (RT), MICT combined with RT, and high-intensity interval training (HIIT) have all been proven to provide clinical benefits for individuals with cardiovascular disease (CVD). However, the effects of HIIT combined with RT on functional capacity outcomes and clinical risk factors outcomes in patients with CVD are not well investigated. Therefore, the purpose of this retrospective cohort study is to investigate the synergistic effects of HIIT combined with RT on functional capacity outcomes including six-minute walk distance (6MWD), peak oxygen uptake (VO2peak), and metabolic equivalent of tasks (METs) and clinical risk factors outcomes including systolic blood pressure, diastolic blood pressure, body weight, waist circumference, body mass index (BMI), and dietary behavior compared to MICT, MICT combined with RT, and HIIT in cardiac rehabilitation (CR) patients with CVD at a single hospital’s CR center, by utilizing secondary CR outcomes data from January 01, 2022, through April 30, 2024. This study included a total of 212 participants distributed as follows: MICT (n=55), MICT+RT (n=50), HIIT (n=53), and HIIT+RT (n=54). To compare the effects of HIIT combined with RT on functional capacity outcomes and clinical risk factors outcomes to MICT, MICT combined with RT, and HIIT, a series of analysis of covariate (ANCOVAs) were conducted. This study found that HIIT combined with RT lead to significantly greater improvements in 6MWD, VO2peak, METs, systolic blood pressure, and waist circumference compared to MICT, MICT combined with RT, and HIIT.

Available for download on Thursday, November 13, 2025

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