Category
Theoretical Proposal
Description
Neuropathic pain is a chronic debilitating condition typically caused by nervous system injury or disease. This experiment proposes that a single subcutaneous injection of formalin is sufficient to produce neuropathic pain and associated nervous tissue changes. It is hypothesized that a western blot of lumbar tissue collected from formalin-injected mice will show an increase of two key proteins indicating gliosis: GFAP and Iba1.
Western Blot Analysis of a Formalin-Induced Neuropathic Pain Model in Mice
Theoretical Proposal
Neuropathic pain is a chronic debilitating condition typically caused by nervous system injury or disease. This experiment proposes that a single subcutaneous injection of formalin is sufficient to produce neuropathic pain and associated nervous tissue changes. It is hypothesized that a western blot of lumbar tissue collected from formalin-injected mice will show an increase of two key proteins indicating gliosis: GFAP and Iba1.
