Category
Oral - Theoretical Proposal
Description
In late 2019 and early 2020, we observed the emergence of Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), which quickly spread around the world, becoming a pandemic and global health crisis. This study, via a literature review, presents an epidemiologic examination of the adverse effects of the mRNA Covid-19 vaccine. Research findings are compiled and compared to better understand the cardiovascular effects of the vaccine from a population level perspective. Incidence and prevalence rates are examined by various demographic factors, primarily age and gender. Specifically, the most prevalent adverse cardiovascular effects noted are myocarditis, pericarditis, cardiovascular disease, tachycardia, hypertension, palpitation, and acute myocardial infarction. Rare cases of disseminated intravascular coagulation and immune thrombocytopenia are observed in older populations. Additionally, men are at a higher risk of developing adverse cardiovascular effects than women; however, several gaps are observed in the literature for other critical demographic variables. First, little research has assessed the relationship between race or ethnicity and adverse cardiovascular effects of the vaccine. Both race and ethnicity have major impacts on vaccine effects due to genetics, culture differences, and vaccine hesitancy. Second, the cardiovascular effects must be examined by the socioeconomic status of the recipient. Socioeconomic status impacts vaccine effects via potential lack of access to healthcare or health education, poor nutrition, and increased suspicion. Due to the novelty of the mRNA Covid-19 vaccine, many studies have focused their data analysis on age or gender characteristics, however many excellent opportunities for future research are necessary to understand the full impact of the vaccine on adverse cardiovascular outcomes at the population level.
Potential Adverse Cardiovascular Side Effects Following mRNA Covid-19 Vaccination
Oral - Theoretical Proposal
In late 2019 and early 2020, we observed the emergence of Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), which quickly spread around the world, becoming a pandemic and global health crisis. This study, via a literature review, presents an epidemiologic examination of the adverse effects of the mRNA Covid-19 vaccine. Research findings are compiled and compared to better understand the cardiovascular effects of the vaccine from a population level perspective. Incidence and prevalence rates are examined by various demographic factors, primarily age and gender. Specifically, the most prevalent adverse cardiovascular effects noted are myocarditis, pericarditis, cardiovascular disease, tachycardia, hypertension, palpitation, and acute myocardial infarction. Rare cases of disseminated intravascular coagulation and immune thrombocytopenia are observed in older populations. Additionally, men are at a higher risk of developing adverse cardiovascular effects than women; however, several gaps are observed in the literature for other critical demographic variables. First, little research has assessed the relationship between race or ethnicity and adverse cardiovascular effects of the vaccine. Both race and ethnicity have major impacts on vaccine effects due to genetics, culture differences, and vaccine hesitancy. Second, the cardiovascular effects must be examined by the socioeconomic status of the recipient. Socioeconomic status impacts vaccine effects via potential lack of access to healthcare or health education, poor nutrition, and increased suspicion. Due to the novelty of the mRNA Covid-19 vaccine, many studies have focused their data analysis on age or gender characteristics, however many excellent opportunities for future research are necessary to understand the full impact of the vaccine on adverse cardiovascular outcomes at the population level.
Comments
Undergraduate - 2nd Place Award Winner