Publication Date
Spring 2020
School
School of Health Sciences
Major
Biology: Biomedical Sciences
Keywords
Celiac disease, Non-Celiac gluten sensitivity, gluten, autoimmune disease, gastrointestinal disease
Disciplines
Food Science | Immunology and Infectious Disease | Medicine and Health Sciences | Nutrition | Physiology
Recommended Citation
Thomas, Victoria, "Comparisons of Celiac Disease and Non-Celiac Gluten Sensitivity" (2020). Senior Honors Theses. 998.
https://digitalcommons.liberty.edu/honors/998
Abstract
Celiac disease (CD) and non-celiac gluten sensitivity (NCGS) are often confused or grouped together due to their commonalities. However, this is careless behavior because there are clinically significant differences between the two diseases. Similarities between them include varying degrees of damage or permeability in the lining of the small intestine, involvement of the innate immune system, alleviation of symptoms upon implementation of a gluten-free diet (GFD), and the possibility for complications if the pathology is not adequately treated. Despite these similarities, minor details such as the following make CD and NCGS worth differentiating: the question of gluten as the true trigger for NCGS, severity of villous atrophy present in only CD, psychiatric comorbidities present in NCGS, and possibility of a less restrictive treatment for NCGS using gluten detoxification.
Included in
Food Science Commons, Immunology and Infectious Disease Commons, Medicine and Health Sciences Commons, Nutrition Commons, Physiology Commons
