Noel PenaFollow

Publication Date

Spring 5-2019


School of Health Sciences




venom, cancer, apoptosis, integrin, angiogenesis, disintegrin, L-amino oxidase, lectin, phospholipase


In the wild, venom is crucial to many snakes’ success as predators. While antivenin research focuses on combatting venoms’ abilities to disrupt physiological processes, new studies are attempting to manipulate these same abilities into anticancer therapies. Given the diversity of neurotoxins, hemotoxins, cytotoxins, and others, every new discovery and development within snake venom research adds to the knowledge base and broadens applicational opportunities. Cancer-related venom research isolates various components, manipulates their interaction with target cancer cell lines, and evaluates how their natural biochemical activity counteracts mechanisms that are integral to tumor development. Several more promising components, namely disintegrins, lectins, oxidases, and phospholipases, have emerged. Summarizing and highlighting recent research of these key components can serve as a springboard for future venom-derived antitumor medicines.