Publication Date

5-2026

School

School of Nursing

Major

Nursing (B.S.N.)

Disciplines

Alternative and Complementary Medicine | Nursing

Abstract

The goal of this review is to answer the question: What dietary changes are most effective in restoring gut dysbiosis in healthy adults? The gut microbiome (GM), a community of microorganisms that colonizes in the gastrointestinal (GI) tract, can become imbalanced, a condition known as dysbiosis, which is associated with an increased risk of dysbiosis-induced disease. Dysbiosis-induced diseases include GI disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), neurological disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), and metabolic disorders such as diabetes and obesity (Shen et al., 2025). Pharmacologic interventions are often not necessary to restore dysbiosis in the GI tract. The literature revealed that microbiota regulators, phytonutrient and micronutrient rich foods, and whole dietary pattern interventions can influence GM composition, diversity, metabolites, and health outcomes. However, the specific changes differ based on the type of dietary interventions and different study variables. The most significant findings included in this integrative review noted changes in composition, diversity, and metabolites after dietary changes. However, only some studies found evidence linking microbiome changes to health outcomes. Further research is needed to investigate the long-term clinical outcomes related to these dietary changes, such as dysbiosis-induced disease.

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