Publication Date
4-2022
School
School of Health Sciences
Major
Biology: Biomedical Sciences
Keywords
T Cell Therapy, Immunology, Cancer
Disciplines
Medical Immunology | Oncology
Recommended Citation
McCloy, Griffin, "T Cell Therapy: Underlying Mechanisms and Current Advancements" (2022). Senior Honors Theses. 1158.
https://digitalcommons.liberty.edu/honors/1158
Abstract
As the second leading cause of death in 2016, cancer is one of the most serious diseases facing the world today. T cell therapy is a current area of research attempting to address the disease with two primary division: CAR-T and TCR-T cell therapy. The immune system naturally produces T lymphocytes to aid in the recognition and removal of cells infected with viruses or transformed into cancer. Under normal circumstances, T lymphocytes identify and destroy cancerous cells; however, some cancerous cell types can evade this system. With the use of genetic editing technology, T lymphocytes can gain the ability to recognize these evasive cancers. The editing process is known as T cell therapy.
