School of Nursing
Doctor of Nursing Practice (DNP)
High Fructose Corn Syrup, Artificial Sweeteners, Diabetes Mellitus Type Two, Hemoglobin A1C, Sucralose, Sucralose-6-acetate, gut microbiota
Glover, Rachelle S., "High Fructose Corn Syrup and Sugar Substitutes: Hemoglobin A1C Implications in Diabetes?" (2023). Doctoral Dissertations and Projects. 4634.
Diabetes mellitus type 2 (DMt2) is an increasing health concern of epidemic proportion in the United States. High fructose corn syrup (HFCS) and artificial sweeteners (AS) have been implicated as contributory factors to DMt2. This project seeks to demonstrate elimination of daily consumption of HFCS and AS in DMt2 patients can contribute to lower hemoglobin A1C (HgbA1C) levels by comparing two groups of patients receiving two differing diabetes education programs. A reduction of HgbA1C levels by 0.2-0.5% is expected in DMt2 patients instructed to eliminate HFCS and AS, and no change is expected in HgbA1C levels in DMt2 patients receiving ADA standards diabetes education alone.