School of Health Sciences
Biology: Biomedical Sciences
organ transplants, immunology
Medicine and Health Sciences
Macpherson, Rachel J., "ABO-incompatible Organs a Viable and Necessary Source for Transplants" (2014). Senior Honors Theses. 429.
Despite the astounding technological advancements of modern society, failure to receive a timely organ transplant accounts for the death of approximately 18 U.S. citizens each day. As the population continues to expand, so does the shortage of donor-recipient matching organs. In order to alleviate this deficit, medical researchers have addressed the most common barrier that accounts for donor-recipient denial: blood typing. Within recent years, immunological understanding has progressed leading researchers to believe ABO-incompatible organs may be a viable source for transplantation with unparalleled potential to expand donor availability. It is the intent of this review to increase public awareness of organ transplant issues, leading to, perhaps a global reorganization and revision of the organ transplantation system.