College of Arts and Sciences
Primary Subject Area
Health Sciences, Epidemiology
Tuberculosis, TB, developing nations, TB drugs
Ott, Sarah, "Tuberculosis In Developing Nations: Why New Drugs Need To Be Researched And Developed" (2008). Senior Honors Theses. 37.
Pharmacologic treatment for tuberculosis is widely available in developing nations, and is often financed by the governments of these countries. Treatment however can be highly toxic and require a lengthy duration of therapy. There are now many strains of tuberculosis that are drug resistant. People in impoverished nations frequently cannot afford to pay for transportation to and from treatment facilities. Research and development of new tuberculosis drugs is necessary given the presence of resistance and toxicity of the existing drugs. Newer agents that require shorter treatment duration with decreased toxicity and increased efficacy are most desirable and needed in developing nations.