Marysol HohlFollow

Publication Date

Fall 11-22-2023


School of Health Sciences


Biology: Biomedical Sciences


Ferroptosis, bacterial infection, antibiotic resistance, microbiology, cell biology, nanomedicine, programmed cell death


Bacterial Infections and Mycoses | Biological Phenomena, Cell Phenomena, and Immunity | Cells | Clinical Epidemiology | Infectious Disease | Medical Microbiology | Pharmaceutics and Drug Design | Quality Improvement


Bacterial infections in the United States are becoming increasingly resistant to existing antibiotic treatments. Due to projected increases in resistance and the recent decrease in novel antibacterials, experts have determined that the United States is in the “post-antibiotic era.” The scientific community has failed to resolve resistance despite the continual discovery of new antibiotic compounds. In the past decade, a novel form of cell death called ferroptosis has been implicated in antibiotic treatment by employing the use of nanotechnology. This literature review will describe the problem of bacterial resistance and demonstrate how current research is pioneering a new age of medicine using ferroptosis and nanotechnology.