School of Health Sciences
Biology: Biomedical Sciences
zebrafish, zebrafish immunity, model organism
Immunology and Infectious Disease
Chembars, Michael Solomon Jr., "Danio rerio: A Past, Present, and Future Hallmark for Immunological Studies" (2022). Senior Honors Theses. 1231.
An emerging species that is slowly gaining reputation as a common model organism is Danio rerio. Due to its similarities to our own immune response and its general ease of use, hundreds of studies have been conducted which have increased our understanding of how chemicals or pathogens can affect both our own health, and the health of the environment.
This study aims to briefly describe a brief history of D. rerio, as well as discuss key experiments that have been performed using D. rerio. A comparison will also be made between the human and zebrafish immune responses, and discuss how future experiments can exploit this similarity to benefit future studies.