School of Health Sciences
Biochemistry and Molecular Biology
Bisphenol A, BPA, oxidative stress, reactive oxygen species, ROS, RONS
Biochemistry | Molecular Biology | Pharmacology, Toxicology and Environmental Health | Toxicology
Nas, Rachel, "An Investigation into the Adverse Effects of Oxidative Stress from Exposure to Bisphenol A and Its Analogues" (2020). Senior Honors Theses. 1017.
Oxidative stress is a physiological event caused by an overaccumulation of reactive oxygen species (ROS) within the body. While ROS are a natural by-product of oxygen metabolism, too many can lead to cell and tissue damage and contribute to many etiologies. Bisphenol A (BPA), a component of many plastic products, has been shown to induce oxidative stress. While the industrial usage of BPA usage has lessened, the safety of its replacements is unknown. This paper will primarily discuss ROS and mechanisms of oxidative stress, the usage of BPA and its analogues, etiologies associated with oxidative stress resulting from exposure to BPA and analogues, and a proposed experimental design to determine oxidative stress from exposure to BPA and its analogues.