Senior Honors Theses

Publication Date

Spring 4-24-2009

School

College of Arts and Sciences

Major

Biology: Pre-Med

Primary Subject Area

Biology, General

Keywords

BPA, Bisphenol A, Zebrafish, Toxicity

Disciplines

Biology

Abstract

Bisphenol A, an estrogen mimicker, is found in the commonly used plastic, polycarbonate. Zebrafish embryos were raised in water that had been heated in polycarbonate water bottles by either microwaving for 5 minutes, or boiling for one hour. Near total mortality was seen in 7 days for the embryos growing in bottle-microwaved water, and 9 days for those raised in bottle-boiled water. Zebrafish embryos were also grown in the following known concentrations of BPA: 2mg/l, 14mg/l, 16mg/l, 50mg/l, 135mg/l, and 235mg/l. A stepwise relationship between concentration of BPA and embryo lifespan was seen, and the lowest observed adverse effect level was at 14mg/l.

Included in

Biology Commons

Share

COinS