Publication Date
Spring 5-1-2018
School
School of Health Sciences
Major
Biology: Biomedical Sciences; Exercise Science: Pre-Professional
Keywords
Spinal, Cord, Spine, Vertebrae, Vertebral, Spinal Cord, Spinal Column, Trauma, Injury, Primary injury, Secondary injury, ROS, Astrogliosis, Glutamate, Exitotoxicity, Free Radical, Glial, Research, Nervous, CNS, Central Nervous, Treatment, Research, Therapy, Therapies
Disciplines
Biology | Critical Care | Emergency Medicine | Medical Anatomy | Medical Cell Biology | Medical Immunology | Medical Neurobiology | Medical Pathology | Medical Physiology | Molecular and Cellular Neuroscience | Musculoskeletal, Neural, and Ocular Physiology | Nervous System | Nervous System Diseases | Neurology | Neurosciences | Orthopedics | Other Medical Sciences | Other Neuroscience and Neurobiology | Other Rehabilitation and Therapy | Pathological Conditions, Signs and Symptoms | Pharmacy and Pharmaceutical Sciences | Sports Medicine | Trauma
Recommended Citation
Morin, Daniel, "Spinal Cord Trauma: An Overview of Normal Structure and Function, Primary and Secondary Mechanisms of Injury, and Emerging Treatment Modalities" (2018). Senior Honors Theses. 746.
https://digitalcommons.liberty.edu/honors/746
Abstract
The structures of the spinal cord and vertebral column are designed to provide flexibility, while still providing ample protection for the spinal cord deep within. While it does offer remarkable protection against most routine trauma, the spinal cord is still vulnerable to high-force etiologies of trauma and may become damaged as a result. These events are referred to as primary injury. Following the initial injury, the body’s own physiological responses cause a cascade of deleterious effects, known as secondary injury. Secondary injury is a major therapeutic target in mitigating the effects of spinal cord injury (SCI), and much research is currently being done to develop more effective treatment options.
Included in
Biology Commons, Critical Care Commons, Emergency Medicine Commons, Medical Anatomy Commons, Medical Cell Biology Commons, Medical Immunology Commons, Medical Neurobiology Commons, Medical Pathology Commons, Medical Physiology Commons, Molecular and Cellular Neuroscience Commons, Musculoskeletal, Neural, and Ocular Physiology Commons, Nervous System Commons, Nervous System Diseases Commons, Neurology Commons, Neurosciences Commons, Orthopedics Commons, Other Medical Sciences Commons, Other Neuroscience and Neurobiology Commons, Other Rehabilitation and Therapy Commons, Pathological Conditions, Signs and Symptoms Commons, Pharmacy and Pharmaceutical Sciences Commons, Sports Medicine Commons, Trauma Commons
