Senior Honors Theses

Publication Date

Spring 2014

School

School of Health Sciences

Major

Biology: Biomedical Sciences

Keywords

organ transplants, immunology

Disciplines

Medicine and Health Sciences

Abstract

Despite the astounding technological advancements of modern society, failure to receive a timely organ transplant accounts for the death of approximately 18 U.S. citizens each day. As the population continues to expand, so does the shortage of donor-recipient matching organs. In order to alleviate this deficit, medical researchers have addressed the most common barrier that accounts for donor-recipient denial: blood typing. Within recent years, immunological understanding has progressed leading researchers to believe ABO-incompatible organs may be a viable source for transplantation with unparalleled potential to expand donor availability. It is the intent of this review to increase public awareness of organ transplant issues, leading to, perhaps a global reorganization and revision of the organ transplantation system.

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