College of Arts and Sciences
Primary Subject Area
Gerontology; Health Sciences, Medicine and Surgery; Health Sciences, Nursing; Health Sciences, Pharmacology
clopidogrel, Plavix, hip fracture, surgery, surgical delay
Geriatric Nursing | Other Nursing | Perioperative, Operating Room and Surgical Nursing | Pharmacy Administration, Policy and Regulation
Waller, Phoebe Genevieve, "Surgical Delay for Hip Fracture Clients and the Use of Clopidogrel: An Integrative Review" (2012). Senior Honors Theses. 274.
Hip fractures in elderly patients have very high postoperative mortality rates and the number of hip fractures in the United States is expected to increase exponentially before 2030. Early surgery is essential to improve outcomes, but patients on clopidogrel (Plavix) have a high risk for increased bleeding if surgery is performed within the usual 72 hour window. This paper presents literature and research addressing the dangers of delaying surgery versus undergoing surgery before the effects of the clopidogrel are gone. Based on articles published after 2006, most researchers advocated earlier surgical intervention than previously recommended and emphasized an individualized approached based on the clients’ comorbidities and susceptibilities to select postoperative complications.