Scientific research does not occur without influence from media and culture. Certainly, changes in funding decisions and publishing patterns are not immune to the influence of a single fantastic case. Andrea Yates' gruesome murder of her five children is just that type of case. The present paper focuses on the influence of that case on postpartum depression research in terms of both content and volume. The explosion of research on postpartum depression since Yates murdered her children is inarguable, the content of that research was organized into three areas: application of postpartum depression, mother-child relationship, and related constructs and discussed in detail.