Research has shown that changes in gene expression play a critical role in the development of Alzheimer’s Disease (AD). Our project will evaluate genome-wide RNA expression patterns from brain and blood in an AD mouse model. This analysis will provide insight regarding the mechanisms of AD pathology as well as determine a possible diagnostic tool utilizing RNA expression patterns found in the blood as biomarkers for AD.
Hazy, Amanda and Dalton, Matthew, "Analysis of Differential mRNA and miRNA Expression in an Alzheimer’s Disease Mouse Model" (2014). Other Undergraduate Scholarship. 1.
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